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Pluris Research, Inc.

A contract research organization CRO specialized in providing pre-clinical studies for consumer, medical, and surgical product research and development.

Pluris Research, Inc. was established in 2001 and is located in Franklin, TN.

We are an independent, private, state of the art surgical research laboratory specialized in providing pre-clinical studies for consumer-medical-surgical product research and development. We are dedicated to our Sponsors providing the best preclinical research support services possible designed for clinical relevance with direct communication with the Study Director throughout the study.

We have many models and years of experience, both clinical and preclinical, in studies for wound healing (dressings, debridement, topicals, collagen, etc.), infection potentiation (antibacterial sutures, dressings, barrier-sealants), implantable devices, bone healing (including fusion), pharmacology (pk and dose response) of pharmaceuticals, systemic toxicity studies, and more. We provide histology, quantitative microbiology, in-vivo biomechanical testing (BTC-2000™, clinical chemistry … and more.

Our models are pre-approved so we can initiate studies without delay. We perform pilot and definitive studies, both non-GLP and GLP. Studies are scientifically designed to evaluate the safety, efficacy, and product performance to support regulatory claims substantiation and FDA submission.

Wound healing:

In-vitro Skin testing for Skin Barriers and Cleansers:

In-vivo Skin Testing, Topical or Technology:

Antibacterial and Antimicrobial Sutures, Surgical Tissue Adhesives, BioFilms, IVs and Dressings:

Wound Hemostasis:

Dressing Adherence Strength:

Bone Allograft, Fillers, and Osteoinductivity:

Implantable Materials, Injectables, Including Local Tolerance and Systemic Toxicity:

Breast Implants, Silicone Cohesive Gel, and Tissue Expanders:

Scanning Electron Microscopy (SEM):

These established models have been used extensively for preclinical evaluation of product performance and are well documented in the literature. Additional models, including custom models, may be considered as required by the Sponsor.


Pluris Research, Inc.

P.O. Box 681967
Franklin, TN 37068 USA
Tel: +1 (615) 776-2823
Fax: +1 (615) 776-2786